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Gremlin 1 antibody

Size Price Availability Qty
100 μg
Usually dispatched within 5-10 working days
Shipping charges : Freight/Packing: $34

Gremlin-1 (Grem1), an antagonist of bone morphogenetic proteins, is involved in fibrotic tissue formation in kidney and lung. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) .Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.

Product Information

Category Primary antibodies
Product name Gremlin 1 antibody
Catalog Number orb10741
Host Rabbit
Clonality Polyclonal
Tested applications WB, IHC-P, IF/ICC
Dilution range IF/ICC: 1:50-500, IHC-P: 1:50-500, WB: 1:200-1500
Concentration - 100 μg (in 200 μl): 0.5 mg/ml
- 200 μg (in 400 μl): 0.5 mg/ml
Reacts with Human, Mouse, Rat, Pig
UniProt ID O60565 (Human); O70326 (Mouse); O35793 (Rat)
Entrez 26585
Conjugation Unconjugated
Immunogen KLH conjugated synthetic peptide derived from human Gremlin 1. Please contact us for the exact immunogen sequence. The peptide is available as orb12894.
Purity Polyclonal antibodies are purified by peptide affinity chromatography
MW 21 kDa
Isotype IgG
Form 10 mM PBS, 0.02% sodium azide
Storage Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Note For research use only.
Target Gremlin 1
Alternative names
anti Grem1 antibody, anti Grem 1 antibody, anti Gremlin1, antibody, anti Cysteine knot superfamily 1 antibody, anti Down-regulated in Mos-transformed cells protein antibody, anti Cktsf1b1 antibody, anti BMP antagonist 1 antibody, anti Drm antibody, anti Cell proliferation inducing gene 2 protein antibody, anti DAND2 antibody, anti Gremlin 1 like protein antibody, anti Gremlin-1 antibody, anti IHG-2 antibody, anti IHG2 antibody, anti Increased in high glucose protein 2 antibody, anti proliferation-inducing gene 2 antibody

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Immunofluorescence analysis of mouse bone marrow tissue using Gremlin 1 antibody (dilution of primary antibody - 2.5 ug/ml)
Immunohistochemical staining of paraffin embedded mouse bone marrow tissue using anti-Gremlin 1 (primary antibody at 2.5 ug/ml)
Immunofluorescence analysis of mouse bone marrow tissue using Gremlin 1 antibody (dilution of primary antibody - 2.5 ug/ml)
Western blot analysis of human lung cancer (lane 1), mouse testis (lane 2), mouse spinal cord (lane 3) using Gremlin 1 antibody (1 ug/ml)
Immunohistochemical staining of paraffin embedded rat pancreas tissue using anti-Gremlin 1 (primary antibody at 2.5 ug/ml)
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